Distinct roles of NMB and GRP in itch transmission.

Wan L, Jin H, Liu XY, Jeffry J, Barry DM, Shen KF, Peng JH, Liu XT, Jin JH, Sun Y, Kim R, Meng QT, Mo P, Yin J, Tao A, Bardoni R, Chen ZF. Distinct roles of NMB and GRP in itch transmission. Sci Rep. 2017 Nov 13;7(1):15466. PMID: 29133874

Read more

Sensory TRP channels contribute differentially to skin inflammation and persistent itch.

Feng J, Yang P, Mack MR, Dryn D, Luo J, Gong X, Liu S, Oetjen LK, Zholos AV, Mei Z, Yin S, Kim BS, Hu H. Sensory TRP channels contribute differentially to skin inflammation and persistent itch. Nat Commun. 2017 Oct 30;8(1):980. PMID: 29081531. PMCID: PMC5661746. 

Read more

Sensory Neurons Co-opt Classical Immune Signaling Pathways to Mediate Chronic Itch.

Oetjen LK, Mack MR, Feng J, Whelan TM, Niu H, Guo CJ, Chen S, Trier AM, Xu AZ, Tripathi SV, Luo J, Gao X, Yang L, Hamilton SL, Wang PL, Brestoff JR, Council ML, Brasington R, Schaffer A, Brombacher F, Hsieh CS, Gereau RW 4th, Miller MJ, Chen ZF, Hu H, Davidson S, Liu Q, Kim BS. Cell. 2017…

Read more

Transient receptor potential vanilloid 4-expressing macrophages and keratinocytes contribute differentially to allergic and nonallergic chronic itch.

Luo J, Feng J, Yu G, Yang P, Mack MR, Du J, Yu W, Qian A, Zhang Y, Liu S, Yin S, Xu A, Cheng J, Liu Q, O'Neil RG,…

Read more

The antimicrobial peptide human beta-defensin 2 promotes itch through Toll-like receptor 4 signaling in mice.

Feng J, Luo J, Mack MR, Yang P, Zhang F, Wang G, Gong X, Cai T, Mei Z, Kim BS, Yin S, Hu H. The antimicrobial peptide human beta-defensin 2…

Read more

Spinal Mechanisms of Itch Transmission

Barry DM, Munanairi A, Chen ZF. Neurosci Bull. 2017 Apr 1. doi: 10.1007/s12264-017-0125-2. [Epub ahead of print] PMID: 28365862.

Read more

Molecular and neural basis of contagious itch behavior in mice.

Yu YQ*, Barry DM*, Hao Y*, Liu XT, Chen ZF. Molecular and neural basis of contagious itch behavior in mice. Science. 2017 Mar 10;355(6329):1072-1076. PMID: 28280205. (*These authors contributed equally to this work.)

Read more

Recent Positive Selection in Genes of the Mammalian Epidermal Differentiation Complex Locus.

Goodwin ZA, de Guzman Strong C. (2017) Recent Positive Selection in Genes of the Mammalian Epidermal Differentiation Complex Locus.Front Genet. 2017 Jan 10;7:227. PMID: 28119736

Read more