Potentiation of high voltage-activated calcium channels by 4-aminopyridine depends on subunit composition.

Li L, Li DP, Chen SR, Chen J, Hu H, Pan HL (2014). Potentiation of high voltage-activated calcium channels by 4-aminopyridine depends upon subunit composition. Mol Pharmacol 86(6): 760-772. PMID:…

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Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity.

Brestoff JR, Kim BS, Saenz SA, Stine RR, Monticelli LA, Sonnenberg GF, Thome JJ, Farber DL, Lutfy K, Seale P, Artis D. Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity. Nature. 2015; 519(7542):242-6. PMID: 25533952. 

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Loureirin B, an essential component of Sanguis Draxonis, inhibits Kv1.3 channel and suppresses cytokine release from Jurkat T cells.

Yin S, Hu Q, Luo J, Li Y, Lu C, Chen X and Hu H (2014). Loureirin B, an essential component of Sanguis Draxonis, inhibits Kv1.3 channel and suppresses cytokine…

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Descending control of itch transmission by the serotonergic system via 5-HT1A-facilitated GRP-GRPR signaling.

Zhao ZQ, Liu XY, Jeffry J, Karunarathne WKA, Li JL, Munanairi A, Zhou XY, Li H, Sun YG, Wan L, Wu ZY, Kim S, Huo FQ, Mo P, Barry DM,…

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Thermally activated TRPV3 channels

Luo J, Hu H (2014). Thermally activated TRPV3 channels. Curr Top Membr 74: 325-364. PMID: 25366242

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Innate Lymphoid Cells in the Skin.

Kim BS. Innate Lymphoid Cells in the Skin. J Invest Dermatol. 2015; 135(3):673-678.

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Peptidomimetics of Arg-Phe-NH2 as small molecule agonists of Mas-related gene C (MrgC) receptors.

Hin N, Alt J, Zimmermann SC, Delahanty G, Ferraris DV, Rojas C, Li F, Liu Q, Dong X, Slusher BS, Tsukamoto T. Peptidomimetics of Arg-Phe-NH2 as small molecule agonists of…

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Cross-Inhibition of NMBR and GRPR Signaling Maintains Normal Histaminergic Itch Transmission.

Zhao ZQ, Wan L, Liu XY, Huo FQ, Li H, Barry DM, Krieger S, Kim S, Liu ZC, Xu J, Rogers BE, Li YQ, Chen ZF. J Neurosci. 2014 Sep 10;34(37):12402-14. 

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Basophils Promote Innate Lymphoid Cell Responses in Inflamed Skin.

Kim BS, Wang K, Siracusa MC, Saenz SA, Brestoff JR, Monticelli LA, Noti M, Tait Wojno ED, Fung TC, Kubo M, Artis D. Basophils Promote Innate Lymphoid Cell Responses in Inflamed Skin. J…

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Epigenetic coordination of embryonic heart transcription by dynamically regulated long noncoding RNAs.

Matkovich SJ, Edwards JR, Grossenheider  TC, de Guzman Strong C, DornII GW (2014) Epigenetic coordination of embryonic heart transcription by dynamically regulated lncRNAs. Proc. Natl. Acad. Sci. 111(33): 12264-9. PMID:25071214

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Activation of MrgC receptor inhibits N-type calcium channels in small-diameter primary sensory neurons in mice.

Li Z, He SQ, Xu Q, Yang F, Tiwari V, Liu Q, et al. Pain. 2014;155(8):1613-21.

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Postnatal maintenance of the 5-Ht1a-Pet1 autoregulatory loop by serotonin in the raphe nuclei of the brainstem.

Kim JY, Kim A, Zhao ZQ, Liu XY, Chen ZF. Mol Brain. 2014;7(1):48.

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Exposure to food allergens through inflamed skin promotes intestinal food allergy through the thymic stromal lymphopoietin-basophil axis.

Noti M, Kim BS, Siracusa MC, Rak GD, Kubo M, Moghaddam AE, Sattentau QA, Comeau MR, Spergel JM, Artis D, Exposure to food allergens through inflamed skin promotes intestinal food…

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LE135, a retinoid acid receptor antagonist, produces pain through direct activation of TRP channels.

Yin S, Luo J, Qian A, Yu W, and Hu H (2014). LE135, a retinoid acid receptor antagonist, produces pain through direct activation of TRP channels.  Br J Pharmacol 171:…

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Dorsal Raphe Neurons Signal Reward through 5-HT and Glutamate.

Liu Z, Zhou J, Li Y, Hu F, Lu Y, Ma M, Feng Q, Zhang JE, Wang D, Zeng J, Bao J, Kim JY, Chen ZF, El Mestikawy S, Luo M. Neuron. 2014; 81(6):1360-74.

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Thymic stromal lymphopoietin variation, filaggrin loss-of-function, and the persistence of atopic dermatitis.

Margolis DJ, Kim B, Apter AJ, Gupta J, Hoffstad O, Papadopoulos M, Mitra N, Thymic stromal lymphopoietin variation, filaggrin loss-of-function, and the persistence of atopic dermatitis, JAMA Dermatol. 2014:150(3):254-9. PMID: 24401911

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MrgC agonism at central terminals of primary sensory neurons inhibits neuropathic pain.

He SQ, Li Z, Chu YX, Han L, Xu Q, Li M, Yang F, Liu Q, Tang Z, Wang Y, Hin N, Tsukamoto T, Slusher B, Tiwari V, Shechter R,…

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Regulation of the dynamic chromatin architecture of the Epidermal Differentiation Complex is mediated by a c-Jun/AP-1-modulated enhancer during skin development.

Oh, I.Y., Albea, D.M., Goodwin, Z.A., Quiggle, A.M., Baker, B.P., Guggisberg, A.M., Kroner, G.M., de Guzman Strong, C. (2014) Regulation of the dynamic chromatin architecture of the Epidermal Differentiation Complex…

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B-type natriuretic peptide is neither itch-specific nor functions upstream of the GRP-GRPR signaling pathway

Liu XY, Wan L, Huo FQ, Barry DM, Li H, Zhao ZQ and Chen ZF. Mol Pain. 2014; 10:4

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CD164 and FCRL3 are highly expressed on CD4+CD26- T cells in Sézary syndrome patients.

Wysocka M, Kossenkov AV, Benoit BM, Troxel AB, Singer E, Schaffer A, Kim B, Dentchev T, Nagata S, Ise T, Showe LC, Rook AH, CD164 and FCRL3 are highly expressed…

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