Targeting Pain-evoking Transient Receptor Potential Channels for the Treatment of Pain.

Luo J, Walters ET, Carlton SM and Hu H (2013). Targeting Pain-evoking Transient Receptor Potential Channels for the Treatment of Pain. Curr Neuropharmacol 11(6):652-63 (invited review). PMID: 24396340

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TSLP-mediated extramedullary hematopoiesis promotes allergic inflammation.

Siracusa MC, Saenz SA, Wojno ED, Kim BS, Osborne LC, Ziegler CG, Benitez AJ, Ruymann KR, Farber DL, Sleiman PM, Hakonarson H, Cianferoni A, Wang ML, Spergel JM, Comeau MR,…

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Chronic itch development in sensory neurons requires BRAF signaling pathways

Zhao ZQ*, Huo FQ*, Jeffry J, Hampton L, Demehri S, Kim S, Liu XY, Barry DM, Wan L, Liu ZC, Li H, Turkoz A, Ma K, Cornelius LA, Kopan R, Battey,…

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Retinoids activate the irritant receptor TRPV1 and produce sensory hypersensitivity.

Yin S*, Luo J*, Qian A, Du J, Yang Q, Zhou S, Yu W, Du G, Clark RB, Walters ET, Carlton SM, and Hu H (2013). Retinoids activate the irritant…

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IL-25 simultaneously elicits distinct populations of innate lymphoid cells and multipotent progenitor type 2 (MPPtype2) cells.

Saenz SA, Siracusa MC, Monticelli LA, Ziegler CG, Kim BS, Brestoff JR, Peterson LW, Wherry EJ, Goldrath AW, Bhandoola A, Artis D, IL-25 simultaneously elicits distinct populations of innate lymphoid…

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Thymic stromal lymphopoietin-elicited basophil responses promote eosinophilic esophagitis.

Noti M, Wojno ED, Kim BS, Siracusa MC, Giacomin PR, Nair MG, Benitez AJ, Ruymann KR, Muir AB, Hill DA, Chikwava KR, Moghaddam AE, Sattentau QJ, Alex A, Zhou C,…

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Intrinsic atopic dermatitis (AD) shows similar Th2 and higher Th17 immune activation compared to extrinsic AD

Suarez-Farinas, M., Dhingra, D., Gittler, J, Shemer, A., Cardinale, I., de Guzman Strong, C., Krueger, J.G., Guttman-Yassky, E.  (2013) Intrinsic atopic dermatitis (AD) shows similar Th2 and higher Th17 immune…

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Cutaneous immunosurveillance and regulation of inflammation by group 2 innate lymphoid cells.

Roediger G, Kyle R, Yip KH, Sumaria N, Guy TV, Kim BS, Mitchell MJ, Tay SS, Jain R, Forbes-Blom E, Chen X, Tong PL, Bolton HA, Artis D, Paul WE, Fazekas…

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Over-Expression of the Gastrin-Releasing Peptide in Cutaneous Nerve Fibers and its Receptor in Spinal Cord in Primates with Chronic Itch.

Nattkemper LA, Zhao ZQ, Nichols AJ, Papoiu AD, Shively CA, Chen ZF, Yosipovitch G. J Invest Dermatol. 2013 Oct;133(10):2489-92

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Translational profiling of hypocretin neurons identifies candidate molecules for sleep regulation.

Dalal, J.  Roh, J.H., Maloney, S.E., Akuffo, A., Shah, S., Yuan, H., Wamsley, B., Jones, W.B., de Guzman Strong, C., Holtzman, D., Heintz, N., Dougherty, J.D.  (2013) Translational profiling of…

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A subpopulation of nociceptors specifically linked to itch

Han L, Ma C, Liu Q, et al. Nature Neuroscience. 2013;16(2):174-82.  

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Scaffolding by A-kinase anchoring protein enhances functional coupling between adenylyl cyclase and TRPV1 channel.

Efendiev R*, Bavencoffe A*, Hu H, Zhu MX, Dessauer CW (2013). Scaffolding by A-kinase anchoring protein enhances functional coupling between adenylyl cyclase and TRPV1 channel. J Biol Chem 288(6): 3929-3937.  PMID: 23264624

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TSLP elicits IL-33-independent innate lymphoid cell responses to promote skin inflammation.

Kim BS, Siracusa MC, Saenz SA, Noti M, Monticelli LA, Sonnenberg GF, Van Voorhees AS, Smith DE, Comeau MR, Artis D, TSLP elicits IL-33-independent innate lymphoid cell responses to promote…

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