Peptidomimetics of Arg-Phe-NH2 as small molecule agonists of Mas-related gene C (MrgC) receptors.

Hin N, Alt J, Zimmermann SC, Delahanty G, Ferraris DV, Rojas C, Li F, Liu Q, Dong X, Slusher BS, Tsukamoto T. Peptidomimetics of Arg-Phe-NH2 as small molecule agonists of…

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Activation of MrgC receptor inhibits N-type calcium channels in small-diameter primary sensory neurons in mice.

Li Z, He SQ, Xu Q, Yang F, Tiwari V, Liu Q, et al. Pain. 2014;155(8):1613-21.

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MrgC agonism at central terminals of primary sensory neurons inhibits neuropathic pain.

He SQ, Li Z, Chu YX, Han L, Xu Q, Li M, Yang F, Liu Q, Tang Z, Wang Y, Hin N, Tsukamoto T, Slusher B, Tiwari V, Shechter R,…

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