The distinct roles of two GPCRs, MrgprC11 and PAR2, in itch and hyperalgesia.
Liu Q*, Weng HJ*, Patel KN*, Tang Z, Bai H, and Dong X. Science Signaling 2011; 4(181):ra45 *Denotes equal contribution (Cover article).
Pirt, a TRPV1 modulator, is required for histamine-dependent and -independent itch.
Patel KN, Liu Q, Meeker S, Undem BJ, Dong X. PLoS ONE. 2011; 6(5):e20559.
TRPA1 is required for histamine-independent, Mas-related G protein-coupled receptor-mediated itch.
Wilson SR, Gerhold KA, Bifolck FA, Liu Q, Patel K, Dong X, Bautista DM. Nature Neuroscience, 2011; 14:595-602