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Brian Kim, MD

Co-Director, Center for the Study of Itch

Assistant Professor of Dermatology


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Biography

Dr. Brian Kim received his B.S. in Chemistry from Haverford College in 2001 and his M.D. from the University of Washington School of Medicine in 2007. He trained under Dr. Stephen Katz in the Dermatology Branch of the National Cancer Institute as a Howard Hughes Medical Institute-National Institutes of Health Research Scholar from 2004-2006. In 2008, he entered his residency in dermatology at the Perelman School of Medicine at the University of Pennsylvania (UPenn) on the physician-scientist track. After completing his residency and his postdoctoral training in the laboratory of Dr. David Artis, he joined the Division of Dermatology at Washington University School of Medicine as an Assistant Professor of Medicine. His research focuses on understanding how the innate immune system regulates immunity and inflammation at the skin barrier surface. He was the first to identify group 2 innate lymphoid cells (ILC2s) in the skin of both mice and humans and implicate them in the pathogenesis of atopic dermatitis (AD). These key discoveries have provoked a number of fundamental questions related to the biology of skin inflammation and its relationship to chronic itch. Future studies investigating the innate immune regulation of skin inflammation may lead to new treatments for chronic itch.


Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity.

Brestoff JR, Kim BS, Saenz SA, Stine RR, Monticelli LA, Sonnenberg GF, Thome JJ, Farber DL, Lutfy K, Seale P, Artis D. Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity. Nature. 2015; 519(7542):242-6. PMID: 25533952. 

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Innate Lymphoid Cells in the Skin.

Kim BS. Innate Lymphoid Cells in the Skin. J Invest Dermatol. 2015; 135(3):673-678.

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Basophils Promote Innate Lymphoid Cell Responses in Inflamed Skin.

Kim BS, Wang K, Siracusa MC, Saenz SA, Brestoff JR, Monticelli LA, Noti M, Tait Wojno ED, Fung TC, Kubo M, Artis D. Basophils Promote Innate Lymphoid Cell Responses in Inflamed Skin. J…

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Exposure to food allergens through inflamed skin promotes intestinal food allergy through the thymic stromal lymphopoietin-basophil axis.

Noti M, Kim BS, Siracusa MC, Rak GD, Kubo M, Moghaddam AE, Sattentau QA, Comeau MR, Spergel JM, Artis D, Exposure to food allergens through inflamed skin promotes intestinal food…

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Thymic stromal lymphopoietin variation, filaggrin loss-of-function, and the persistence of atopic dermatitis.

Margolis DJ, Kim B, Apter AJ, Gupta J, Hoffstad O, Papadopoulos M, Mitra N, Thymic stromal lymphopoietin variation, filaggrin loss-of-function, and the persistence of atopic dermatitis, JAMA Dermatol. 2014:150(3):254-9. PMID: 24401911

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CD164 and FCRL3 are highly expressed on CD4+CD26- T cells in Sézary syndrome patients.

Wysocka M, Kossenkov AV, Benoit BM, Troxel AB, Singer E, Schaffer A, Kim B, Dentchev T, Nagata S, Ise T, Showe LC, Rook AH, CD164 and FCRL3 are highly expressed…

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CBS news: Finding new ways to combat chronic itch

Watch here

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Potential new therapy relieves chronic itch

Congratulations to Dr. Brian Kim's team!

Dr. Brian Kim, dermatologist, and Landon Oetjen, MD/PhD student, of the CSI discover highly promising new pathway for the treatment of chronic itch. Please read news Record, Daily Mail.

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BBC interview: Itchy and Scratchy

"What is an itch and how does scratching stop it? Why does scratching some itches feel so good?!" asks Xander Tarver from Wisborough Green in West Sussex.

Our doctors set off to probe the mysteries of itch, and discover that this overlooked area of medicine is revealing surprising results about the human brain. From why itching is contagious to why scratching is pleasurable, we get under the skin of this medical mystery.

The programme features interview with dermatologist Dr Brian Kim from…

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Brian Kim Discusses Itch on Great Day St. Louis

What's the Itch? Dr. Brian Kim explains some reasons why you can't get rid of the itch. Watch video here.

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Brian Kim named the recipient of 2016 Clinical Scientist Development Award by DDCF, Congratulations!

Dr. Brian Kim won the prestigious 2016 Clinical Scientist Development Award, according to The Doris Duke Charitable Foundation's announcement.  He is one of the 17 exceptional physician scientists selected from 169 applicants by a panel of experts in medical experts. Congratulations to Dr. Brian Kim!  Please read DDCF award announcement here.

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