BrianKim

Brian Kim, MD

Co-Director, Center for the Study of Itch

Assistant Professor of Dermatology


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Biography

Dr. Brian Kim is Assistant Professor of Dermatology, Anesthesiology, Pathology and Immunology, and Co-Director of the Center for the Study of Itch at Washington University School of Medicine in St. Louis. His laboratory focuses on innate immune mechanisms that underlie skin inflammation and the sensation of itch. Specifically, the Kim Lab identified previously unrecognized contributions of group 2 innate lymphoid cells (ILC2s) and basophils to the pathogenesis of atopic dermatitis (AD) in both mice and humans. These cells have emerged as critical sources of the type 2 cytokines IL-4, IL-5, and IL-13, which are now among the most important targets for biologic therapy in AD and other allergic disorders. More recently, the Kim Lab was the first to identify functionality of IL-4 receptor alpha (IL-4R) and Janus kinases (JAKs) in sensory neurons as master regulators of chronic itch in AD and other disorders. These studies have immediate clinical implications as type 2 cytokine and JAK blockade have emerged as some of the most efficacious therapeutics in AD. His research on the immune regulation of AD and itch has led to awards and funding from the National Institutes of Health, Doris Duke Charitable Foundation, American Skin Association, American Academy of Dermatology, and the American Society for Clinical Investigation.


TSLP promotes interleukin-3-independent basophil haematopoiesis and type 2 inflammation.

Siracusa MC, Saenz SA, Hill DA, Kim BS, Headley MB, Doering TA, Wherry EJ, Jessup HK, Siegel LA, Kambayashi T, Dudek EC, Kubo M, Cianferoni A, Spergel JM, Ziegler SF,…

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Potential new therapy relieves chronic itch

Congratulations to Dr. Brian Kim's team!

Dr. Brian Kim, dermatologist, and Landon Oetjen, MD/PhD student, of the CSI discover highly promising new pathway for the treatment of chronic itch. Please read news Record, Daily Mail.

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CBS news: Finding new ways to combat chronic itch

Watch here

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BBC interview: Itchy and Scratchy

"What is an itch and how does scratching stop it? Why does scratching some itches feel so good?!" asks Xander Tarver from Wisborough Green in West Sussex.

Our doctors set off to probe the mysteries of itch, and discover that this overlooked area of medicine is revealing surprising results about the human brain. From why itching is contagious to why scratching is pleasurable, we get under the skin of this medical mystery.

The programme features interview with dermatologist Dr Brian Kim from…

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Brian Kim Discusses Itch on Great Day St. Louis

What's the Itch? Dr. Brian Kim explains some reasons why you can't get rid of the itch. Watch video here.

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Brian Kim named the recipient of 2016 Clinical Scientist Development Award by DDCF, Congratulations!

Dr. Brian Kim won the prestigious 2016 Clinical Scientist Development Award, according to The Doris Duke Charitable Foundation's announcement.  He is one of the 17 exceptional physician scientists selected from 169 applicants by a panel of experts in medical experts. Congratulations to Dr. Brian Kim!  Please read DDCF award announcement here.

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