Center for the Study of Itch

The Center for the Study of Itch seeks to understand the fundamental underlying mechanisms of itch and translate these findings into treatments for patients suffering from intractable itch.

Learn more 

Center for the Study of Itch

The Center for the Study of Itch seeks to understand the fundamental underlying mechanisms of itch and translate these findings into treatments for patients suffering from intractable itch.

Learn more 


 See All News

CSI News

Itching for no reason? Immune system may be at fault

In a small study of patients who have chronic itching with no known cause, researchers from Dr. Brian Kim's lab at the Center for the Study of Itch identified immune system irregularities that may prompt the urge to scratch.

Read the news here. Watch FOX2now TV news here.

Read More 

Brian Kim wins St. Louis Business Journal’s 2016 40 Under 40 award, Congratulations!

Each year the St. Louis Business Journal selects and honors the best and brightest leaders under 40 in the St. Louis metropolitan region.  This year, Dr. Brian Kim, Co-Director of CSI, has been chosen as one of 40 honorees from 650 nominations.  Dr. Brian Kim is recognized for his ability to bridge basic and translational research in chronic itch. For details, please read: St. Louis Business Journal,         Dr. Brian Kim.

Read More 

Qin Liu named a 2015 Pew Scholar, Congratulations!

Qin Liu is among 22 outstanding young scientists named the 2015 class of Pew Scholar in the Biomedical Sciences by the Pew Charitable Trusts. Congratulations to Qin Liu for her achievement ! 

Read the news at the Pew Biomedical Scholars.

Read More 

Why scratching makes you itch more?

Read the story in The Record. Watch the video abstract here.

Also in the News:
NBC Nightly News (video)Inside science (video)D News (video)NZ 3 News (video)ScoopStop (video)AAAS (podcast)BBCHuffington PostThe TelegraphThe Washington PostThe Daily MailNew ScientistThe IndependentScience News, Mirror, IFL Science, Fox NewsDermatology TimesPsychology Today.

Read More 

New York Times Features Innovative Research at CSI

In a recent interview with The New York Times, Drs. Zhou-Feng Chen and Lynn Cornelius, talk about chronic itch as an unmet need and the clinical implication of the discovery of an itch-specific receptor called GRPR.

Read The New York Time article "Itching: more than deep-skin".

 

Read More 

 See All Publications

Recent Publications

New insights into basophil heterogeneity.

Oetjen LK, Noti M, Kim BS. New insights into basophil heterogeneity. Semin Immunopathol. 2016 May 13. [Epub ahead of print] PMID: 27178409

See details 

Immune dysregulation underlies a subset of patients with chronic idiopathic pruritus.

Xu AZ, Tripathi SV, Kau AL, Schaffer A, Kim BS. Immune dysregulation underlies a subset of patients with chronic idiopathic pruritus. J Am Acad Dermatol.  2016 May;74(5):1017-20. PMID: 27085236

See details 

Critical evaluation of the expression of gastrin-releasing peptide in dorsal root ganglia and spinal cord.


Barry DM, Li H, Liu XY, Shen KF, Liu XT, Wu ZY, Munanairi A, Chen XJ, Yin J, Sun YG, Li YQ, Chen ZF. Mol Pain. 2016 Apr 11;12. pii: 1744806916643724. doi: 10.1177/1744806916643724. Print 2016 Feb.

See details 

A histamine-independent itch pathway is required for allergic ocular itch.

Huang CC, Kim YS, Olson WP, Li F, Guo C, Luo W, Huang AJ, Liu Q. A histamine-independent itch pathway is required for allergic ocular itch. J Allergy Clin Immunol. 2015 Oct 28. pii: S0091-6749(15)01343-3. doi: 10.1016/j.jaci.2015.08.047. [Epub ahead of print] PubMed PMID: 26521042.

See details 

Molecular and cellular mechanisms that initiate pain and itch.

Luo J, Feng J, Liu S, Walters ET, Hu H (2015). Molecular and cellular mechanisms that initiates pain and itch. Cell and Mol Life Sci 72(17):3201-23. PMID: 25894692

See details 

Low Filaggrin Monomer Repeats in African American Pediatric Patients With Moderate to Severe Atopic Dermatitis.

Quiggle AM, Goodwin ZA, Marfatia TR, Kumar MG, Ciliberto H, Bayliss SJ, de Guzman Strong C. (2015) Low filaggrin monomer repeats in African-American pediatric patients with moderate to severe atopic dermatitis. JAMA Dermatology, 2015; 151(5):557-9. PMID:25564772

See details 

Innate Lymphoid Cells in the Skin.

Kim BS. Innate Lymphoid Cells in the Skin. J Invest Dermatol. 2015; 135(3):673-678.

See details